Vaccination Schedule for Dogs and Cats in the U.S.

Vaccination Schedule for Dogs and Cats in the U.S. (2025 Guide)
Vaccinations are essential to keep your pets safe from deadly diseases and ensure a healthy, long life. In the U.S., pet vaccinations are not only recommended but in some states, they are legally required. Whether you’re a new pet parent or updating your pet’s health records, this guide will walk you through the current vaccination schedules for dogs and cats in 2025.
Why Pet Vaccinations Matter
Vaccines stimulate your pet’s immune system to recognize and combat infectious diseases. Without vaccinations, dogs and cats are vulnerable to viruses like rabies, distemper, and feline leukemia, which can be fatal.
Benefits of Vaccination:
- Prevents deadly diseases
- Reduces long-term healthcare costs
- Protects other pets and humans
- May be required for boarding, grooming, or travel
Dog Vaccination Schedule (2025)
Vaccines for dogs are divided into core and non-core (optional) based on risk and exposure.
Core Vaccines for Dogs
These are essential for all dogs, regardless of location or lifestyle.
Vaccine | Initial Dose | Booster Schedule | Notes |
---|---|---|---|
Rabies | 12-16 weeks | 1 year later, then every 1–3 years | Legally required in all U.S. states |
DHPP (Distemper, Hepatitis, Parvovirus, Parainfluenza) | 6–8 weeks, 10–12 weeks, 14–16 weeks | 1 year later, then every 3 years | Also called “5-in-1” shot |
Non-Core Vaccines for Dogs
Recommended based on environment, location, and lifestyle.
Vaccine | Initial Dose | Booster Schedule | Best For |
Bordetella (Kennel Cough) | 6–8 weeks | Annually | Dogs in daycare, boarding, or dog parks |
Lyme Disease | 12 weeks, then 3-4 weeks later | Annually | Dogs in tick-heavy regions (Northeast, Midwest) |
Leptospirosis | 12 weeks, then 3-4 weeks later | Annually | Dogs exposed to water sources or wildlife |
Canine Influenza | 6–8 weeks, then 2-4 weeks later | Annually | Dogs in large groups or urban areas |
Cat Vaccination Schedule (2025)
Like dogs, cats have core and non-core vaccines.
Core Vaccines for Cats
Vaccine | Initial Dose | Booster Schedule | Notes |
Rabies | 12–16 weeks | 1 year later, then every 1–3 years | Required in most states |
FVRCP (Feline Viral Rhinotracheitis, Calicivirus, Panleukopenia) | 6–8 weeks, then every 3–4 weeks until 16 weeks | 1 year later, then every 3 years | Also known as the “3-in-1” vaccine |
Non-Core Vaccines for Cats
Vaccine | Initial Dose | Booster Schedule | Best For |
Feline Leukemia (FeLV) | 8 weeks, then 3–4 weeks later | Annually | Outdoor cats or those in multi-cat homes |
Chlamydia felis | 6–8 weeks | Annually | Cats in high-risk environments |
Bordetella bronchiseptica | 8 weeks | Annually | Cats in shelters or boarding |
Tips for Pet Parents in the U.S.
- Follow Your Vet’s Advice: Always consult your veterinarian to personalize your pet’s vaccine plan.
- Keep Records: Maintain a copy of all vaccination certificates. Required for boarding, travel, and grooming.
- Watch for Side Effects: Mild reactions are normal (e.g., lethargy, soreness), but report any swelling or severe behavior changes to your vet.
- State Laws Differ: For example, some states require annual rabies shots while others accept 3-year intervals.
- Consider Lifestyle: Indoor-only pets may need fewer vaccines than pets that travel or go outdoors often.
FAQs About Pet Vaccinations in the U.S.
Q: Are pet vaccinations required by law? A: Rabies vaccination is legally required for both dogs and cats in most U.S. states.
Q: Can I vaccinate my pet at home? A: Some vaccines can be administered at home, but rabies must be given by a licensed vet.
Q: What’s the cost of pet vaccinations in the U.S.? A: Core vaccines typically cost $20–$40 per shot; full vaccine packages may cost $75–$200 annually.
Q: Are vaccine titers a substitute? A: Titers test immunity levels and may be accepted by some vets instead of re-vaccination, especially for DHPP and FVRCP.
Final Thoughts
Staying current with your pet’s vaccinations is a responsible and loving choice. With proper scheduling and regular vet visits, you can ensure your dog or cat is protected from preventable diseases. Use this 2025 U.S. guide to plan your pet’s health journey and consult your vet for any adjustments.